2. Meiosis karyotyping and non-disjunction

• Biologie
• Middelbare school
• vwo
• Leerjaar 4

How many cell divisions are there in meiosis?

1. 1
2. 2
3. 3
4. 4

In the first meiotic division...

1. Sister chromatids separate
2. Homologous chromosomes separate

In the second meiotic division...

1. Sister chromatids separate
2. Homologous chromosomes separate

What are the products of meiosis?

1. Two diploid (2n) cells
2. Four diploid (2n) cells
3. Two haploid (n) cells
4. Four haploid (n) cells

23 pairs of homologous chromosomes

46 chromosomes in total

Have you heard of chromosomal abnormalities?

Yes

No

Of which chromosomal abnormalities have you heard?

In the following slides, in which chromosome pair can you spot the aneuploidy?

What about the other chromosomes?
Do they also have aneuploidies?
Where are they?

Creates sperm and egg cells (gametes)

1. Mitosis
2. Meiosis
3. Both

Produces two diploid (2n) daughter cells

1. Mitosis
2. Meiosis
3. Both

Involves two successive cell divisions

1. Mitosis
2. Meiosis
3. Both

Creates a human cell with 23 pairs of chromosomes

1. Mitosis
2. Meiosis
3. Both

Starts with a diploid parent cell

1. Mitosis
2. Meiosis
3. Both

Daughter cells are genetically different

1. Mitosis
2. Meiosis
3. Both

Cells undergo DNA replication

1. Mitosis
2. Meiosis
3. Both

Recombination of genetic information through crossing-over

1. Mitosis
2. Meiosis
3. Both

When I order a passport, I must tick a box male/female
What do I tick if my child has Klinefelter syndrome?

Male

Female

Both