5.5 When genes change

5. It runs in the family
On inheritance, family trees, genetics and DNA

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This lesson contains 11 slides, with text slides and 1 video.

time-iconLesson duration is: 45 min

Items in this lesson

5. It runs in the family
On inheritance, family trees, genetics and DNA

Slide 1 - Slide

5.5 when genes change
    What is a mutation?
    How can a disease be inherited from one generation to the   
    next?

Slide 2 - Slide

mutations
= change in a gene or chromosome (genotype)

This may result in no/small/large change in phenotype

Slide 3 - Slide

mutations
= change in a gene or chromosome (genotype)

This may result in no/small/large change in phenotype

the change can be negative/neutral/beneficial

Slide 4 - Slide

mutations 

Slide 5 - Slide

Slide 6 - Video

mutations 
External caused by known mutagens 
  • Radiation: (eg. UV light, X-ray, radioactive decay)
  • Chemicals (eg. benzene in cigarette smoke)
  • Bacteria or viruses (eg. HPV)
Internal
  • DNA replication




Slide 7 - Slide

mutations 
Gene mutations
    Defect of a gene
    eg. sickle cell disease
Chromosome mutations
    Change in a whole chromosome
     eg. extra chromosome 21 leads to Down Syndrome


Slide 8 - Slide

Definitions
A= healthy
a = sickle cell disease

Person with AA is healthy
Person with aa has sickle cell disease
Person with Aa is a 'carrier'

Slide 9 - Slide

Genetic counselor
role play

Project starts in two weeks
You''l become a genetic counselor. A couple with a child's wish will visit you. You have to advice them on the probabilities of having a baby with a genetic disease
 

Slide 10 - Slide

Read section 5.5
Do exercises 30, 31, 32 (34, 35 and 36)

Slide 11 - Slide