Exploring Coarse Dispersions in Physical Pharmaceutics
Exploring Coarse Dispersions in Physical Pharmaceutics
Learning objective
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Exploring Coarse Dispersions in Physical Pharmaceutics
Learning objective
Learning Objective
At the end of the lesson, you will understand the properties, applications, and stability factors of coarse dispersions in pharmaceutics.
What do you already know about coarse dispersions in pharmaceutics?
Definition of Coarse Dispersions
Coarse dispersions consist of large particles dispersed in a continuous phase. They include suspensions and emulsions.
Properties of Coarse Dispersions
These dispersions have large particle sizes, typically over 1 micrometer, and are visible to the naked eye.
Applications in Pharmaceutics
Coarse dispersions are used in topical formulations, oral suspensions, and injectable drugs.
Stability Factors
Key factors include particle size, zeta potential, and viscosity. These affect dispersion stability.
Common Challenges
Sedimentation, creaming, and phase separation can occur, affecting drug efficacy.
Improving Stability
Use surfactants, thickeners, and homogenization to enhance dispersion stability.
Interactive Activity
Group discussion: Analyze a case study of a pharmaceutical coarse dispersion.
Write down 3 things you learned in this lesson.
Write down 2 things you want to know more about.
Ask 1 question about something you haven't quite understood yet.
