V4 Inheritance 5

• Biologie
• Middelbare school
• vwo
• Leerjaar 4

The lesson will start once everyone has done the following:

- Open your macbook

- Open the Huntington's disease assignment

- Join the lessonup

- Put away phones etc.

- Direct attention towards the front of the classroom

Program for today:

First half, with the whole group:

• short discussion Huntington's assignment
• overview of where we are in the Inheritance block
• demonstration of Punnett square for a dihybrid cross

*break*

Second half, individually or in small groups:

• practice with dihybrid cross
• practice with sex-linked inheritance

Huntington's Disease assignment: discussion

Expectations:

• Have joined the lessonup
• Have the assignment open on your computer
• Give each other room to talk and be heard; listen
• Actively participate

Advice: read the introduction properly!

What are the chances that the child from the assignment will get Huntington's disease?

1. 1/4
2. 1/3
3. 1/2
4. 3/4

Is there a difference in risk between a boy (with XY) and a girl (with XX)?

1. yes
2. no

Why isn't it possible to be a carrier for Huntington's?

What was the most important factor in your decision to have children or not?

How do you calculate probabilities for a dihybrid cross?

Inheritance: what have we done so far and what is still to come?

Done:

• Vocabulary: genes, alleles, homozygous, heterozygous, dominant, recessive, carrier...
• Incomplete dominance
• Monohybrid crosses

Started:

• Dihybrid crosses
• Sex-linked inheritance (X-chromosomal)

Still to come:

• Co-dominance
• Multiple alleles
• Lethal alleles
• (Epigenetics)

Flexible work time:

- First priority: Complete the dihybrid cross worksheet

- Second priority: Complete the worksheet sex-linked inheritance

- Optional: 

• extra exercises dihybrid cross
• choose an article about genetics to read (see Classroom)
• help your classmates

You may work together (put everyone's names in the worksheet title)