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YR3-K16-LSN4
HAVE READY
JOIN THIS LESSONUP
YOUR NOTEBOOK
KERBOODLE PAGE 254
GOOGLE CLASROOM
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Slide 1:
Tekstslide
Biologie
Middelbare school
havo, vwo
Leerjaar 3
In deze les zitten
38 slides
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interactieve quizzen
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HAVE READY
JOIN THIS LESSONUP
YOUR NOTEBOOK
KERBOODLE PAGE 254
GOOGLE CLASROOM
Slide 1 - Tekstslide
PLAN FOR TODAY:
CHECK IN CLASS ASSIGNMENTS LESSON 2
HW FOR LESSON 4 (ANY QUESTIONS)
PRACTICE QUESTIONS
IN CLASS ASSIGNMENTS LESSON 4
Slide 2 - Tekstslide
ASSIGNMENTS DURING LESSON 2
CHECK THE ANSWERS
ASK QUESTIONS
Slide 3 - Tekstslide
I know what mutations are and how they can occur.
I know what (types of) tumors there are and how they can affect the body.
I understand how cancer works and how it can be treated.
I can use a punnet square to show the inheritance of certain genes.
I know how to calculate the chances of various possible outcomes with genetic disorders.
I understand what various inherited diseases are and how they can be passed on in families.
MUTATIONS
MUTANT
ALBINO
CYSTIC FIBROSIS
HUNTINGTON’S DISEASE
SICKLE CELL ANAEMIA
COLOUR BLINDNESS
TUMORS
CANCER
MALIGNANT
BENIGN
METASTASIZE
KERBOODLE P. 254-255
Slide 4 - Tekstslide
Steps with Punnet Squares
Identify your alleles.
Identify genotype parent 1. Show possible gametes.
Identify genotype parent 2. Show possible gametes.
Fill in your punnet squares.
Write down ratios of the possible genotypes.
Write down ratios of the possible phenotypes.
Slide 5 - Tekstslide
PRACTICE ASSIGNMENTS
INHERITANCE
Slide 6 - Tekstslide
Test cross
How to know if an organism is heterozygous (Rr) or homozygous (RR)?
--> crossing the unknown parent with a
homozygous recessive
parent
Slide 7 - Tekstslide
Mutations
= a change in a gene/chromosome that can cause a change in a characteristic
change in the DNA base sequence
--> gene codes for another
characteristic
-->
MUTANT (mostly recessive)
Slide 8 - Tekstslide
Mutations - albinism
Normal gene produces melanin pigment (protects against UV)
Mutated gene doen't produce melanin
Slide 9 - Tekstslide
10
Slide 10 - Video
02:14
What would be step 1a for this cross?
Slide 11 - Open vraag
02:30
What would be step 1b for this cross?
Slide 12 - Open vraag
02:44
What would be step 2 for this cross?
Slide 13 - Open vraag
03:10
What would be step 3 for this cross?
Slide 14 - Open vraag
03:27
What are the chances of a hairless cat in this cross?
A
0 %
B
25 %
C
50 %
D
75 %
Slide 15 - Quizvraag
Mutations - antibiotics resistance
Mutant gene codes for a protein that breaks down the antibiotics
Slide 16 - Tekstslide
Slide 17 - Tekstslide
Inherited diseases to know
1. Cystic fibrosis
2. Huntington's disease
3. Sickle cell anaemia
4. Colour blindness
Slide 18 - Tekstslide
1. Cystic fibrosis
Recessive disease caused by a gene mutation, risk 1/2000
Thick, sticky mucus blocks air passages + digestive tubes
Respiratory and digestive problems
Antibiotics, chest physio, gene therapy (inhaling correct genes)
Heterozygous Cc = carriers, homozygous recessive cc = sufferers
Slide 19 - Tekstslide
Cystic fibrosis
Slide 20 - Tekstslide
2. Huntington's disease
Dominant disease, risk 1/20,000
Degeneration of brain cells -> movement, memory disorders
Heterozygous Hh + homozygous dominant HH = sufferers
Late disease onset (>30-40y)
Slide 21 - Tekstslide
3. Sickle cell anaemia
Recessive genetic disease
Sickle shaped RBC with abnormal haemoglobin -> O
2
transport problems
West Africa
homozygous recessive = affected
heterozygous = carrier (resistant to malaria!)
Slide 22 - Tekstslide
3. Sickle cell anaemia
Slide 23 - Tekstslide
4. Colour blindness
Recessive allele on x-chromosome
more in male (only one X)
Slide 24 - Tekstslide
4. Colour blindness
Slide 25 - Tekstslide
Genetic engineering
Removing a gene from an organism and putting it in another
Eg: making insulin in diabetes patients
Slide 26 - Tekstslide
Selective breeding
Artificial selection
-> improves characteristics in
plants and animals, usually for
human benefit
-> humans determine passed
on alleles to next generation
Slide 27 - Tekstslide
Slide 28 - Tekstslide
Cancer
10% of all cancers are genetic
mutation in genes that control the way cells grow and multiply
Leading to uncontrolled cell growth -> tumor
Slide 29 - Tekstslide
Slide 30 - Tekstslide
Cancer
Slide 31 - Tekstslide
05:42
What possible gene combinations can you come up with for parent 2?
Slide 32 - Open vraag
05:59
Step 4
Please draw this punnet square in your notebook and try to complete it.
Slide 33 - Tekstslide
06:35
What would be step 5 for this cross?
Slide 34 - Open vraag
06:54
What would be step 6 for this cross?
Slide 35 - Open vraag
07:12
What are the chances of an offspring like Moo?
A
0 %
B
25 %
C
50 %
D
75 %
Slide 36 - Quizvraag
ASSIGNMENTS FOR LESSON 4:
START AT THE LEVEL THAT APPLIES TO YOU
THEY MUST BE COMPLETED BEFORE THE NEXT LESSON
FIRST 10 MINUTES IN SILENCE, THEN YOU CAN DISCUSS AND ASK QUESTIONS
Slide 37 - Tekstslide
STUDY FOR THE TESTWEEK:
STUDY FOR THE GLOSSARY QUIZ
STUDY THE WRTS LSN 1-3
STUDY YOUR NOTES
STUDY THE IN CLASS ASSIGNMENTS
Slide 38 - Tekstslide
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