5.3 Genes and DNA

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Slide 1: Tekstslide
BiologieMiddelbare schoolvwoLeerjaar 3

In deze les zitten 25 slides, met interactieve quizzen, tekstslides en 2 videos.

time-iconLesduur is: 45 min

Onderdelen in deze les

Slide 1 - Tekstslide

Slide 2 - Tekstslide

today''s program 


learning objectives : you are able to answer the questions ... 
  • what is DNA made of?
  • how can DNA store information?
  • what is a gene? 
  • what is the link between gene, protein and phenotype? 




Slide 3 - Tekstslide

DNA-chromosomes, genes and traits 
  • While watching the video, listen carefully!
  • Write down the meaning of things and how they are connected. Use the concept list!
  • Stay focussed! (9 min.) 
  • Write down all the questions that you have!
  • Write down the things that you need extra explanation on!

Slide 4 - Tekstslide

Slide 5 - Video

Write down all the questions that you have!

Slide 6 - Woordweb

Slide 7 - Tekstslide

today''s program 


learning objectives : you are able to answer the questions ... 
  • what is DNA made of?
  • how can DNA store information?
  • what is a gene? 
  • what is the link between gene, protein and phenotype? 




Slide 8 - Tekstslide

Mutations

Slide 9 - Tekstslide

Learning Objectives
You can explain what a mutation is.
You can explain how a disease can be inherited from one generation to the next.

Slide 10 - Tekstslide

Slide 11 - Video

Slide 12 - Tekstslide

Mutations
= change in a gene or chromosome (genotype).

Somatic mutations can cause cancer, for example UV-light can cause skin cancer.

Germline mutations may result in no/small/large change in phenotype.

Slide 13 - Tekstslide

Mutations
= change in a gene or chromosome (genotype)

This may result in no/small/large change in phenotype

the change can be negative/neutral/beneficial

Slide 14 - Tekstslide

Mutations 

Slide 15 - Tekstslide

Mutations 
External caused by known mutagens 
  • Radiation: (eg. UV light, X-ray, radioactive decay)
  • Chemicals (eg. benzene in cigarette smoke)
  • Bacteria or viruses (eg. HPV)
Internal
  • DNA replication




Slide 16 - Tekstslide

Mutations 
Gene mutations
    Defect of a gene
    eg. sickle cell disease
Chromosome mutations
    Change in a whole chromosome
     e.g. extra chromosome 21 leads to Down Syndrome


Slide 17 - Tekstslide

Slide 18 - Tekstslide

Why do you think that Huntington’s disease is still around (1 in 20.000 people) whereas other dominantly inherited diseases are not that common?

Slide 19 - Open vraag

A man who gets Huntington’s disease at the age of 40 had two children with a woman who doesn’t have it. He had himself tested and he turns out to be a heterozygote. What is the chance both his children will get it? Explain by using Punnett squares.

Slide 20 - Open vraag

Slide 21 - Tekstslide

Slide 22 - Tekstslide

A man who is a carrier of cystic fibrosis wants to have a child with a woman whose parents are carriers of cystic fibrosis. She doesn’t know if she is a carrier. What is the chance that the child will get cystic fibrosis? Is it advisable to get herself tested?

Slide 23 - Open vraag

Learning Objectives
You can explain what a mutation is.
You can explain how a disease can be inherited from one generation to the next.

Slide 24 - Tekstslide

questions...
  • How many sex chromosomes are there to be found in a gamete? 
  • What are the chances of having a baby girl of baby boy?
  • Who is ‘responsible’ for the gender of a baby: the mother, the father or both?

Slide 25 - Tekstslide