Enzymes and Metabolism

Enzymes and Metabolism
1 / 15
volgende
Slide 1: Tekstslide

In deze les zitten 15 slides, met interactieve quizzen en tekstslides.

Onderdelen in deze les

Enzymes and Metabolism

Slide 1 - Tekstslide

Deze slide heeft geen instructies

Learning Objectives
At the end of the lesson, you will understand the role of enzymes in metabolic processes.
At the end of the lesson, you will be able to distinguish between anabolic and catabolic reactions.
At the end of the lesson, you will recognize the structure and function of enzymes as globular proteins.
At the end of the lesson, you will comprehend the interactions between substrates and enzymes for catalysis.
At the end of the lesson, you will understand the effects of temperature, pH, and substrate concentration on enzyme activity.
At the end of the lesson, you will be able to describe the methods of measuring enzyme-catalyzed reactions.
At the end of the lesson, you will understand how enzymes affect the activation energy of chemical reactions.

Slide 2 - Tekstslide

Deze slide heeft geen instructies

What do you already know about enzymes and metabolism?

Slide 3 - Woordweb

Deze slide heeft geen instructies

The role of enzymes in metabolism
Enzymes are biological catalysts crucial for metabolism, a network of chemical reactions in living organisms.

Slide 4 - Tekstslide

Deze slide heeft geen instructies

Anabolic and catabolic reactions
Metabolism consists of anabolic reactions that build larger molecules from smaller ones using energy, and catabolic reactions that break down larger molecules, releasing energy.

Slide 5 - Tekstslide

Deze slide heeft geen instructies

Enzymes as globular proteins with an active site
Enzymes are globular proteins with an active site where substrates bind, undergoing induced-fit binding which alters both the substrate and active site for catalysis.

Slide 6 - Tekstslide

Deze slide heeft geen instructies

Induced-fit model of enzyme binding
Enzyme activity is influenced by molecular motion, with substrate–active site collisions necessary for catalysis.

Slide 7 - Tekstslide

Deze slide heeft geen instructies

Molecular motion and substrate–active site collisions
Enzyme–substrate specificity is determined by the active site's shape and chemical properties, with denaturation occurring when the enzyme's structure is altered beyond repair.

Slide 8 - Tekstslide

Deze slide heeft geen instructies

Effects of temperature, pH, and substrate concentration on enzyme activity
Temperature, pH, and substrate concentration significantly affect enzyme activity, each with an optimal range for maximum activity.

Slide 9 - Tekstslide

Deze slide heeft geen instructies

Measurements in enzyme-catalyzed reactions
Enzyme-catalyzed reactions are measured by monitoring changes in substrate or product concentration over time.

Slide 10 - Tekstslide

Deze slide heeft geen instructies

Effect of enzymes on activation energy
Enzymes lower the activation energy required for reactions, increasing reaction rates without altering the net energy released.

Slide 11 - Tekstslide

Deze slide heeft geen instructies

Key Definitions
Metabolism: The set of life-sustaining chemical transformations within the cells of living organisms.
Anabolic Reactions: Metabolic reactions that construct molecules from smaller units, requiring energy input.
Catabolic Reactions: Metabolic reactions that break down molecules into smaller units and release energy.
Enzymes: Proteins that act as biological catalysts to speed up chemical reactions without being consumed.
Active Site: The region on an enzyme where substrate molecules bind and undergo a chemical reaction.
Induced-Fit Binding: A model describing how enzyme and substrate undergo shape changes for effective binding and catalysis.
Denaturation: The process by which a protein loses its three-dimensional structure and function, often irreversible.
Activation Energy: The minimum quantity of energy that the reacting species must possess in order to undergo a specified reaction.

Slide 12 - Tekstslide

Deze slide heeft geen instructies

Write down 3 things you learned in this lesson.

Slide 13 - Open vraag

Have students enter three things they learned in this lesson. With this they can indicate their own learning efficiency of this lesson.
Write down 2 things you want to know more about.

Slide 14 - Open vraag

Here, students enter two things they would like to know more about. This not only increases involvement, but also gives them more ownership.
Ask 1 question about something you haven't quite understood yet.

Slide 15 - Open vraag

The students indicate here (in question form) with which part of the material they still have difficulty. For the teacher, this not only provides insight into the extent to which the students understand/master the material, but also a good starting point for the next lesson.