YR3_CH10_LSN4_Innate immunity

LESSON 4
CHAPTER 10

INNATE IMMUNITY
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Slide 1: Tekstslide
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In deze les zitten 28 slides, met interactieve quizzen, tekstslides en 1 video.

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LESSON 4
CHAPTER 10

INNATE IMMUNITY

Slide 1 - Tekstslide

Homework for today

  1. Review the homework with table mates.
  2. Help each other out with problems/questions.
  3. Discussion on the matters that remain.


timer
5:00

Slide 2 - Tekstslide

Learning goals

  • I understand the difference in innate and adaptive immune system
  • I understand the difference in specific and aspecific immune system
  • I can explain what barriers in the human body contribute to immunity
  • I can explain how phagocytes contribute to immunity


Slide 3 - Tekstslide

Keywords

Innate immunity
Adaptive immunity
Barrier function
Phagocyte
Phagocytosis
Lymphatic system
Lymph nodes


Slide 4 - Tekstslide

Innate immunesystem

Parts of the immune system that are present from birth

Slide 5 - Tekstslide

Adaptive immunesystem

Parts and processes of the immune system that are changing based on previous experiences

Slide 6 - Tekstslide

Lines of defence

The immune system counters attacks from pathogens in three lines of defense:

1. Barriers:           keeping the pathogens out
2. Phagocytes:   attacking and wiping out invaded pathogens 
3. Lymphocytes:    learning from phagocytes how to specifically                                      and effectively kill a certain type of pathogen

Slide 7 - Tekstslide

To what part of the immune system do these lines of defence belong?
Innate immune system
Adaptive immune system
Barriers
Phagocytes
Lymphocytes

Slide 8 - Sleepvraag

Lines of defence

Slide 9 - Tekstslide

Line 1: Barriers

Keeping pathogens out
  • skin
  • mucosal membranes
  • stomach acid
  • antibacterial proteins

Slide 10 - Tekstslide

Note locations in your body that are lined by a mucosal membrane

Slide 11 - Woordweb

Line 1: Barriers

Mechanical barriers                   vs               Chemical barriers
Physical blockages preventing pathogens from entering the body



Attacking pathogens by means of antimicrobial molecules

Slide 12 - Tekstslide

As part of innate immunity, the human body utilises mechanical and chemical immunity Which of the following is an example of chemical immunity?
A
Skin
B
Fluid flow in the urinary tracht
C
Stomach acid
D
Mucosal layer in the vagina

Slide 13 - Quizvraag

Explain how washing your skin with soap regularly is countering your immunity.

Slide 14 - Open vraag

Slide 15 - Video

Line 2: phagocytes

phagocytes are able to perform phagocytosis

Slide 16 - Tekstslide

Note the names of the different types of leukocytes that play a part in your innate immunity

Slide 17 - Woordweb

different types of phagocytes

dendritic cells
macrophages
neutrophils
phagocytes that display parts of pathogen on there membranes for display and presentation
phagocytes that patrol in tissues and kill off pathogens. They can be controlled by lymphocytes (line 3)
phagocytes that kill off pathogens by killing themselves

Slide 18 - Tekstslide

1
2
3
Surviving tissue cells are sending out distress molecules
macrophages respond and start to devour the pathogens. They also send out other alarm molecules
neutrophils respond and leave the blood vessels. They attack the pathogen by releasing toxic molecules and they kill themselves off

Slide 19 - Sleepvraag

Overview of line 2

Line 1 fails: pathogens invade the body
Surviving tissue cells call for help
Macrophages start to devour pathogens and send out signs
Neutrophils arrive and join the battle. They massively kill off the pathogens and themselves
Proteins of the complement system start to kill pathogens by perforating them
Dendritic cells display parts of the pathogens on their membranes and travel to the lymph nodes
Activation of defence line 3: the adaptive immune system - the lymphocytes

Slide 20 - Tekstslide

Inflammation

a reaction from the tissue to the signaling molecules

Slide 21 - Tekstslide

Inflammation causes a lot of discomfort. Still it is very useful: for what purpose does tissue get inflamed?

Slide 22 - Open vraag

What is the main 'ingredient' of pus?
A
pathogens
B
macrophages
C
neutrophils

Slide 23 - Quizvraag

Lymphatic system

lymph vessels, lymph nodes, bone marrow, spleen and thymus
sewage system of your body

drained tissue fluid is sent to lymph nodes for screening

here the dendritic cell presents its pathogen parts (antigens)

Slide 24 - Tekstslide

Learning goals

  • I understand the difference in innate and adaptive immune system
  • I understand the difference in specific and aspecific immune system
  • I can explain what barriers in the human body contribute to immunity
  • I can explain how phagocytes contribute to immunity


Slide 25 - Tekstslide

Keywords

Innate immunity
Adaptive immunity
Barrier function
Phagocyte
Phagocytosis
Lymphatic system
Lymph nodes


Slide 26 - Tekstslide

A concept map

A concept map adds descriptions to links between two terms

Slide 27 - Tekstslide

HW for lesson 5

  • Create a concept map on the INNATE IMMUNE SYSTEM of the human body.
  • Hand it in on the google class room before the start of lesson 5.


Slide 28 - Tekstslide